|
Arthrotec |
|
90
Arthrotec 50mg |
|
|
180
Arthrotec 50mg |
|
270
Arthrotec 50mg |
|
90
Arthrotec 75mg |
|
120
Arthrotec 75mg |
|
180 Arthrotec
75mg |
Medication Arthrotec Side Effects:
When
Arthrotec is first started, some people may experience side
effects - including abdominal pain, diarrhea, upset stomach,
nausea and gas - which can occur more frequently than with
diclofenac alone.
These side effects are usually minor, and will usually go away
after a few days as your body adjusts to the new medication. The
pain relief and stomach protection you may receive from
Arthrotec typically outweighs these initial side effects you may
experience, however if side effects persist, please contact your
doctor.
Other potential serious side effects of NSAIDs
As with other NSAID-containing products, serious kidney
reactions have been reported rarely. Some significant increases
in liver tests have occurred, and rare serious liver reactions
have also been reported.
Since serious side effects are still possible with Arthrotec,
you should report any signs or symptoms of gastrointestinal
ulceration or bleeding, skin rash, weight gain or swelling to
your physician. If signs of liver toxicity occur such as nausea,
fatigue, lethargy, itching, jaundice, right upper quadrant
tenderness, and "flu-like" symptoms, you should stop therapy and
seek immediate medical attention.
If you have questions about side effects, please be sure to ask
your doctor or healthcare professional.
Precautions on using Arthrotec
Arthrotec
should not be taken by women who are pregnant or who may become
pregnant. Arthrotec can cause miscarriage, often associated with
bleeding, which may result in other serious complications.
Arthrotec should not be taken by patients with hypersensitivity
to diclofenac or misoprostol or other prostaglandins and in
patients who have experienced asthma, hives, or other
allergic-type reactions after taking aspirin or other NSAIDs.
Rare, life threatening allergic reactions to diclofenac sodium
have been reported.
Medication Arthrotec Drug Interaction:
Aspirin:
Concomitant administration of Arthrotec and aspirin is not
recommended because diclofenac sodium is displaced from its
binding sites by aspirin, resulting in lower
plasma concentrations, peak plasma levels and AUC values.
Digoxin: Elevated digoxin levels have been reported inpatients
receiving digoxin and diclofenac sodium. Patients receiving
digoxin and Arthrotec should be monitored forpossible digoxin
toxicity .Antihypertensive agents: NSAIDs can inhibit the
activity ofantihypertensives, including ACE inhibitors. Thus,
caution should be taken when administering Arthrotec with such
agents. Warfarin: The effects of warfarin and NSAIDs on GI
bleeding are synergistic, such that users of both drugs together
have a risk of serious bleeding greater than users of either
drug alone. Oral hypoglycemics: Diclofenac sodium does not alter
glucose metabolism in healthy people nor does it alter the
effects of oral hypoglycemic agents. There are rare reports,
however, from marketing experience, of changes in effects of
insulin or oral hypoglycemic agents in the presence of
diclofenac sodium that necessitated change in the doses of such
agents. Both hypo- and hyperglycemic effects have been reported.
A direct causal relationship has not been established, but
physicians should consider the possibility that diclofenac
sodium may alter a diabetic patient’s response to insulin or
oral hypoglycemic agents.
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